Isolation and analysis of inhibitors of transposon Tn3 site-specific recombination.
We have constructed a genetic bioassay for inhibitors of site-specific recombination by transposon Tn3 resolvase. Of 6,000 compounds tested, 26 inhibited in vivo, and 5 of these 26 inhibited in vitro. At least two inhibitors also inhibit the topoisomerase of resolvase. We have also identified analog...
Shranjeno v:
| izdano v: | J Bacteriol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1984
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6330043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.159.1.404-406.1984 |
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