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Isolation and analysis of inhibitors of transposon Tn3 site-specific recombination.

We have constructed a genetic bioassay for inhibitors of site-specific recombination by transposon Tn3 resolvase. Of 6,000 compounds tested, 26 inhibited in vivo, and 5 of these 26 inhibited in vitro. At least two inhibitors also inhibit the topoisomerase of resolvase. We have also identified analog...

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書誌詳細
出版年:J Bacteriol
主要な著者: Fennewald, M A, Capobianco, J
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6330043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.159.1.404-406.1984
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