Isolation and analysis of inhibitors of transposon Tn3 site-specific recombination.

We have constructed a genetic bioassay for inhibitors of site-specific recombination by transposon Tn3 resolvase. Of 6,000 compounds tested, 26 inhibited in vivo, and 5 of these 26 inhibited in vitro. At least two inhibitors also inhibit the topoisomerase of resolvase. We have also identified analog...

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Detaylı Bibliyografya
Asıl Yazarlar: Fennewald, M A, Capobianco, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1984
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC215648/
https://ncbi.nlm.nih.gov/pubmed/6330043
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