Loss of polyadenylation protein τCstF-64 causes spermatogenic defects and male infertility

Polyadenylation, the process of eukaryotic mRNA 3′ end formation, is essential for gene expression and cell viability. Polyadenylation of male germ cell mRNAs is unusual, exhibiting increased alternative polyadenylation, decreased AAUAAA polyadenylation signal use, and reduced downstream sequence el...

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Bibliografiska uppgifter
Huvudupphovsmän: Dass, Brinda, Tardif, Steve, Park, Ji Yeon, Tian, Bin, Weitlauf, Harry M., Hess, Rex A., Carnes, Kay, Griswold, Michael D., Small, Christopher L., MacDonald, Clinton C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154438/
https://ncbi.nlm.nih.gov/pubmed/18077340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707589104
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