Loss of polyadenylation protein τCstF-64 causes spermatogenic defects and male infertility

Polyadenylation, the process of eukaryotic mRNA 3′ end formation, is essential for gene expression and cell viability. Polyadenylation of male germ cell mRNAs is unusual, exhibiting increased alternative polyadenylation, decreased AAUAAA polyadenylation signal use, and reduced downstream sequence el...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dass, Brinda, Tardif, Steve, Park, Ji Yeon, Tian, Bin, Weitlauf, Harry M., Hess, Rex A., Carnes, Kay, Griswold, Michael D., Small, Christopher L., MacDonald, Clinton C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154438/
https://ncbi.nlm.nih.gov/pubmed/18077340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707589104
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