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The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity
Cleavage and polyadenylation (C/P) of mRNA is an important cellular process that promotes increased diversity of mRNA isoforms and could change their stability in different cell types. The cleavage stimulation factor (CstF) complex, part of the C/P machinery, binds to U- and GU-rich sequences locate...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294498/ https://ncbi.nlm.nih.gov/pubmed/30257008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky862 |
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