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The Hinge Domain of the Cleavage Stimulation Factor Protein CstF-64 Is Essential for CstF-77 Interaction, Nuclear Localization, and Polyadenylation

Because polyadenylation is essential for cell growth, in vivo examination of polyadenylation protein function has been difficult. Here we describe a new in vivo assay that allows structure-function assays on CstF-64, a protein that binds to pre-mRNAs downstream of the cleavage site for accurate and...

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Detalhes bibliográficos
Main Authors: Hockert, J. Andrew, Yeh, Hsiang-Jui, MacDonald, Clinton C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804217/
https://ncbi.nlm.nih.gov/pubmed/19887456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061705
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