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The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity

Cleavage and polyadenylation (C/P) of mRNA is an important cellular process that promotes increased diversity of mRNA isoforms and could change their stability in different cell types. The cleavage stimulation factor (CstF) complex, part of the C/P machinery, binds to U- and GU-rich sequences locate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Grozdanov, Petar N, Masoumzadeh, Elahe, Latham, Michael P, MacDonald, Clinton C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294498/
https://ncbi.nlm.nih.gov/pubmed/30257008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky862
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