Loss of polyadenylation protein τCstF-64 causes spermatogenic defects and male infertility

Polyadenylation, the process of eukaryotic mRNA 3′ end formation, is essential for gene expression and cell viability. Polyadenylation of male germ cell mRNAs is unusual, exhibiting increased alternative polyadenylation, decreased AAUAAA polyadenylation signal use, and reduced downstream sequence el...

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Hlavní autoři: Dass, Brinda, Tardif, Steve, Park, Ji Yeon, Tian, Bin, Weitlauf, Harry M., Hess, Rex A., Carnes, Kay, Griswold, Michael D., Small, Christopher L., MacDonald, Clinton C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154438/
https://ncbi.nlm.nih.gov/pubmed/18077340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707589104
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