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Gating and Inward Rectifying Properties of the MthK K(+) Channel with and without the Gating Ring

In MthK, a Ca(2+)-gated K(+) channel from Methanobacterium thermoautotrophicum, eight cytoplasmic RCK domains form an octameric gating ring that controls the intracellular gate of the ion conduction pore. The binding of Ca(2+) ions to the RCK domains alters the conformation of the gating ring, there...

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Autors principals: Li, Yang, Berke, Ian, Chen, Liping, Jiang, Youxing
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154359/
https://ncbi.nlm.nih.gov/pubmed/17261840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609655
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