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Gating and Inward Rectifying Properties of the MthK K(+) Channel with and without the Gating Ring

In MthK, a Ca(2+)-gated K(+) channel from Methanobacterium thermoautotrophicum, eight cytoplasmic RCK domains form an octameric gating ring that controls the intracellular gate of the ion conduction pore. The binding of Ca(2+) ions to the RCK domains alters the conformation of the gating ring, there...

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Bibliographic Details
Main Authors: Li, Yang, Berke, Ian, Chen, Liping, Jiang, Youxing
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154359/
https://ncbi.nlm.nih.gov/pubmed/17261840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609655
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