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Gating and Inward Rectifying Properties of the MthK K(+) Channel with and without the Gating Ring
In MthK, a Ca(2+)-gated K(+) channel from Methanobacterium thermoautotrophicum, eight cytoplasmic RCK domains form an octameric gating ring that controls the intracellular gate of the ion conduction pore. The binding of Ca(2+) ions to the RCK domains alters the conformation of the gating ring, there...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154359/ https://ncbi.nlm.nih.gov/pubmed/17261840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609655 |
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