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Acetylcholine Receptor Gating: Movement in the α-Subunit Extracellular Domain
Acetylcholine receptor channel gating is a brownian conformational cascade in which nanometer-sized domains (“Φ blocks”) move in staggering sequence to link an affinity change at the transmitter binding sites with a conductance change in the pore. In the α-subunit, the first Φ-block to move during c...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151656/ https://ncbi.nlm.nih.gov/pubmed/18040059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709858 |
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