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Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure

The amyloid hypothesis of Alzheimer's toxicity has undergone a resurgence with increasing evidence that it is not amyloid fibrils but a smaller oligomeric species that produces the deleterious results. In this paper we address the mechanism of this toxicity. Only oligomers increase the conducta...

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Autors principals: Sokolov, Yuri, Kozak, J. Ashot, Kayed, Rakez, Chanturiya, Alexandr, Glabe, Charles, Hall, James E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151594/
https://ncbi.nlm.nih.gov/pubmed/17101816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609533
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