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Interaction of Acid-sensing Ion Channel (ASIC) 1 with the Tarantula Toxin Psalmotoxin 1 is State Dependent

Acid-sensing ion channels (ASICs) are Na(+) channels gated by extracellular H(+). Six ASIC subunits that are expressed in neurons have been characterized. The tarantula toxin psalmotoxin 1 has been reported to potently and specifically inhibit homomeric ASIC1a and has been useful to characterize ASI...

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Autors principals: Chen, Xuanmao, Kalbacher, Hubert, Gründer, Stefan
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151504/
https://ncbi.nlm.nih.gov/pubmed/16505147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509409
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