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Screening for engineered neomycin riboswitches that control translation initiation
Riboswitches are genetic control elements that regulate gene expression in a small molecule-dependent way. We developed a two-stage strategy of in vitro selection followed by a genetic screen and identified several artificial small molecule-binding riboswitches that respond to the aminoglycoside neo...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151025/ https://ncbi.nlm.nih.gov/pubmed/18000033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.772408 |
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