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Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR

RNA aptamers are in vitro–selected binding domains that recognize their respective ligand with high affinity and specificity. They are characterized by complex three-dimensional conformations providing preformed binding pockets that undergo conformational changes upon ligand binding. Small molecule-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wunnicke, Dorith, Strohbach, Denise, Weigand, Julia E., Appel, Bettina, Feresin, Emiliano, Suess, Beatrix, Müller, Sabine, Steinhoff, Heinz-Jürgen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004059/
https://ncbi.nlm.nih.gov/pubmed/21097555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2222811
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