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Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR
RNA aptamers are in vitro–selected binding domains that recognize their respective ligand with high affinity and specificity. They are characterized by complex three-dimensional conformations providing preformed binding pockets that undergo conformational changes upon ligand binding. Small molecule-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3004059/ https://ncbi.nlm.nih.gov/pubmed/21097555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2222811 |
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