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Tetracycline Determines the Conformation of Its Aptamer at Physiological Magnesium Concentrations

Synthetic riboswitches are versatile tools for the study and manipulation of biological systems. Yet, the underlying mechanisms governing its structural properties and regulation under physiological conditions are poorly studied. We performed spectroscopic and calorimetric experiments to explore the...

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Publicat a:Biophys J
Autors principals: Reuss, Andreas J., Vogel, Marc, Weigand, Julia E., Suess, Beatrix, Wachtveitl, Josef
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269781/
https://ncbi.nlm.nih.gov/pubmed/25517161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.001
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