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Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast

Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre-mRNA splicing in yeast. Efficient regulation is o...

詳細記述

保存先:
書誌詳細
主要な著者: Weigand, Julia E., Suess, Beatrix
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2007
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1919484/
https://ncbi.nlm.nih.gov/pubmed/17567606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm425
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