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Thermodynamic characterization of an engineered tetracycline-binding riboswitch

Riboswitches reflect a novel concept in gene regulation that is particularly suited for technological adaptation. Therefore, we characterized thermodynamically the ligand binding properties of a synthetic, tetracycline (tc)-binding RNA aptamer, which regulates gene expression in a dose-dependent man...

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Main Authors: Müller, Michael, Weigand, Julia E., Weichenrieder, Oliver, Suess, Beatrix
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463898/
https://ncbi.nlm.nih.gov/pubmed/16707663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl347
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