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Purification, crystallization and preliminary X-ray crystallographic analysis of mammalian MSS4–Rab8 GTPase protein complex

Rab GTPases function as ubiquitous key regulators of membrane-vesicle transport in eukaryotic cells. MSS4 is an evolutionarily conserved protein that binds to exocytotic Rabs and facilitates nucleotide release. The MSS4 protein in complex with nucleotide-free Rab8 GTPase has been purified and crysta...

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Detalhes bibliográficos
Main Authors: Itzen, Aymelt, Bleimling, Nathalie, Ignatev, Alexander, Pylypenko, Olena, Rak, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150963/
https://ncbi.nlm.nih.gov/pubmed/16511278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105042995
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