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Purification, crystallization and preliminary X-ray crystallographic analysis of Rab27a GTPase in complex with exophilin4/Slp2-a effector

By switching between GTP-active and GDP-inactive conformations, small Ras GTPases partly regulate membrane trafficking, cell growth and cytoskeleton dynamics. Among Rab GTPases, the Rab27 subfamily, which comprises Rab27a and Rab27b, controls the proper targeting of secretory vesicles to the plasma...

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Detalhes bibliográficos
Main Authors: Chavas, Leonard M. G., Ihara, Kentaro, Kawasaki, Masato, Kato, Ryuichi, Izumi, Tetsuro, Wakatsuki, Soichi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443971/
https://ncbi.nlm.nih.gov/pubmed/18607085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108009251
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