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Hypoxic radiosensitizers: prospects for effective compounds with fewer toxic side-effects.

Several radiosensitizing chemicals, including a family of simple nitroimidazoles, were examined in E. coli and compared with misonidazole for toxic side-effects on endpoints such as mutagenesis, cell killing and inhibition of the synthesis of the inducible enzyme beta-galactosidase. While all the co...

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Autors principals: Rupp, W. D., Mroczkowski, Z., Agrawal, K. C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1978
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149403/
https://ncbi.nlm.nih.gov/pubmed/98175
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