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Radiosensitization and Hypoxic Cell Toxicity of NLA‐1 and NLA‐2, Two New Bioreductive Compounds

Two new bioreductive compounds, 9‐[3‐(2‐nitro‐l‐imidazolyl)propylamino]acridine hydrochloride (NLA‐1) and 9‐[2‐(2‐nitro‐l‐imidazoryl)ethylamino]acridine hydrochloride (NLA‐2), have been prepared. They feature an acridine ring to intercalate with DNA, a 2‐nitroimidazole ring as the radiosensitizing m...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Papadopoulou, Maria V., Epperly, Michael W., Shields, Donna S., Bloomer, William D.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918828/
https://ncbi.nlm.nih.gov/pubmed/1506276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb00123.x
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