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Polyfunctional radiosensitizers IV. The effect of contact time and temperature on sensitization of hypoxic Chinese hamster cells in vitro by bifunctional nitroxyl compounds.

Three biradical nitroxyl compounds have been shown to modify the slope and shoulder region of the hypoxic cell survival curve of V79 cells to different degrees. The amount of sensitization produced by these compounds is dependent on the cell-drug contact time at both 20 degree and 37 degree C wherea...

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Detalhes bibliográficos
Main Authors: Millar, B. C., Fielden, E. M., Smithen, C. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149385/
https://ncbi.nlm.nih.gov/pubmed/277261
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