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Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain

β1A integrin subunits with point mutations of the cytoplasmic domain were expressed in fibroblasts derived from β1-null stem cells. β1A in which one or both of the tyrosines of the two NPXY motifs (Y783, Y795) were changed to phenylalanines formed active α5β1 and α6β1 integrins that mediated cell ad...

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Bibliografske podrobnosti
Main Authors: Sakai, Takao, Zhang, Qinghong, Fässler, Reinhard, Mosher, Deane F.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148458/
https://ncbi.nlm.nih.gov/pubmed/9548729
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