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Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1

Inactivation of maturation-promoting factor [(MPF) Cdk1/Cyclin B] is a key event in the exit from mitosis. Although degradation of Cyclin B is important for MPF inactivation, recent studies indicate that Cdk1 phosphorylation and inactivation occur before Cyclin B degradation and, therefore, also may...

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Detalhes bibliográficos
Main Authors: Forester, Craig M., Maddox, Jessica, Louis, Justin V., Goris, Jozef, Virshup, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148389/
https://ncbi.nlm.nih.gov/pubmed/18056802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709879104
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