טוען...

β cell-specific deficiency of the stimulatory G protein α-subunit G(s)α leads to reduced β cell mass and insulin-deficient diabetes

The G protein α-subunit G(s)α is required for hormone-stimulated cAMP generation. In pancreatic β cells, G(s)α mediates the signaling of glucagon-like peptide 1 and other incretin hormones, which are implicated as important regulators of β cell survival and insulin release. Studies have suggested th...

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מידע ביבליוגרפי
Main Authors: Xie, Tao, Chen, Min, Zhang, Qing-Hong, Ma, Zheng, Weinstein, Lee S.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148335/
https://ncbi.nlm.nih.gov/pubmed/18029451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704796104
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