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The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins
The GNAS1 gene encodes the α subunit of the G protein G(s), which couples receptor binding by several hormones to activation of adenylate cyclase. Null mutations of GNAS1 cause pseudohypoparathyroidism (PHP) type Ia, in which hormone resistance occurs in association with a characteristic osteodystro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21457/ https://ncbi.nlm.nih.gov/pubmed/9707596 |
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