Gene Dosage Effects at the Imprinted Gnas Cluster

Genomic imprinting results in parent-of-origin-dependent monoallelic gene expression. Early work showed that distal mouse chromosome 2 is imprinted, as maternal and paternal duplications of the region (with corresponding paternal and maternal deficiencies) give rise to different anomalous phenotypes...

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Detalhes bibliográficos
Main Authors: Ball, Simon T., Kelly, Michelle L., Robson, Joan E., Turner, Martin D., Harrison, Jackie, Jones, Lynn, Napper, Diane, Beechey, Colin V., Hough, Tertius, Plagge, Antonius, Cattanach, Bruce M., Cox, Roger D., Peters, Jo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688811/
https://ncbi.nlm.nih.gov/pubmed/23822972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065639
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