Wordt geladen...

Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.

We have determined the three-dimensional solution structure of the complex of Lactobacillus casei dihydrofolate reductase and the anticancer drug trimetrexate. Two thousand seventy distance, 345 dihedral angle, and 144 hydrogen bond restraints were obtained from analysis of multidimensional NMR spec...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Polshakov, V. I., Birdsall, B., Frenkiel, T. A., Gargaro, A. R., Feeney, J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144292/
https://ncbi.nlm.nih.gov/pubmed/10091649
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!