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Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.

Thrombin, a trypsin-like serine protease present in blood, plays a central role in the regulation of thrombosis and hemostasis. A cyclic pentapeptide, cyclotheonamide A (CtA), isolated from sponges of the genus Theonella, inhibits thrombin, trypsin, and certain other serine proteases. Enzyme inhibit...

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Hlavní autoři: Ganesh, V., Lee, A. Y., Clardy, J., Tulinsky, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143408/
https://ncbi.nlm.nih.gov/pubmed/8732754
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