Lanean...

Modulation of antibody affinity by a non-contact residue.

Antibody LB4, produced by a spontaneous variant of the murine anti-digoxin monoclonal antibody 26-10, has an affinity for digoxin two orders of magnitude lower than that of the parent antibody due to replacement of serine with phenylalanine at position 52 of the heavy chain variable region (Schildba...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schillbach, J. F., Near, R. I., Bruccoleri, R. E., Haber, E., Jeffrey, P. D., Novotny, J., Sheriff, S., Margolies, M. N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 1993
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142342/
https://ncbi.nlm.nih.gov/pubmed/8443598
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