26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
We have determined the three-dimensional structures of the antigen-binding fragment of the anti-digoxin monoclonal antibody 26-10 in the uncomplexed state at 2.7 A resolution and as a complex with digoxin at 2.5 A resolution. Neither the antibody nor digoxin undergoes any significant conformational...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10310 |
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