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S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease

Peroxiredoxins (Prx), a family of peroxidases that reduce intracellular peroxides with the thioredoxin system as the electron donor, are highly expressed in various cellular compartments. Among the antioxidant Prx enzymes, Prx2 is the most abundant in mammalian neurons, making it a prime candidate t...

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Detalhes bibliográficos
Main Authors: Fang, Jianguo, Nakamura, Tomohiro, Cho, Dong-Hyung, Gu, Zezong, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141847/
https://ncbi.nlm.nih.gov/pubmed/18003920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705904104
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