Growth inhibition of non-small-cell lung carcinoma by BN/GRP antagonist is linked with suppression of K-Ras, COX-2, and pAkt

Bombesin (BN) or gastrin-releasing peptide (GRP) can stimulate the growth of neoplasms such as breast cancer and small-cell lung carcinoma (SCLC). Antagonists of BN/GRP have been shown to inhibit these cancers. We evaluated whether antagonists of BN/GRP can suppress the growth of human non-SCLC (NSC...

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Detalhes bibliográficos
Main Authors: Hohla, Florian, Schally, Andrew V., Kanashiro, Celia A., Buchholz, Stefan, Baker, Benjamin, Kannadka, Chandrika, Moder, Angelika, Aigner, Elmar, Datz, Christian, Halmos, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141835/
https://ncbi.nlm.nih.gov/pubmed/18003891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709455104
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