Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel

We investigated the effect of antagonists of growth hormone-releasing hormone (GHRH) MZ-J-7-138 and JV-1-92 on H460 human non-small cell lung carcinoma (NSCLC) xenografted orthotopically into nude mice. Treatment with MZ-J-7-138 or JV-1-92 inhibited orthotopic growth of H460 NSCLC by 52–65% (P <...

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Autors principals: Hohla, Florian, Schally, Andrew V., Szepeshazi, Karoly, Varga, Jozsef L., Buchholz, Stefan, Köster, Frank, Heinrich, Elmar, Halmos, Gabor, Rick, Ferenc G., Kannadka, Chandrika, Datz, Christian, Kanashiro, Celia A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599991/
https://ncbi.nlm.nih.gov/pubmed/16983095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605309103
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