Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancers

We investigated the efficacy of a powerful antagonist of bombesin/gastrin-releasing peptide (BN/GRP) RC-3940-II administered as a single agent or in combination with cytotoxic agents on the growth of HT-29, HCT-116 and HCT-15 human colon cancer in vitro and in vivo. GRP-receptor mRNA and protein wer...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rick, Ferenc G., Buchholz, Stefan, Schally, Andrew V., Szalontay, Luca, Krishan, Awtar, Datz, Christian, Stadlmayr, Andreas, Aigner, Elmar, Perez, Roberto, Seitz, Stephan, Block, Norman L., Hohla, Florian
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404878/
https://ncbi.nlm.nih.gov/pubmed/22751419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20900
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki