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Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells

BACKGROUND: The telomeric region of mouse chromosome 12 has previously shown frequent allelic loss in murine lymphoma. The Bcl11b gene has been identified and suggested as a candidate tumor suppressor gene within this region. In this study, we aimed to elucidate whether Bcl11b is mutated in lymphoma...

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Autores principales: Karlsson, Anneli, Nordigården, Amanda, Jönsson, Jan-Ingvar, Söderkvist, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140266/
https://ncbi.nlm.nih.gov/pubmed/17941976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-195
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