A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene

Obligatory homologous recombination (HR) is required for chiasma formation and chromosome segregation in meiosis I. Meiotic HR is initiated by DNA double-strand breaks (DSBs), generated by Spo11, a homologue of the archaebacterial topoisomerase subunit Top6A. In Saccharomyces cerevisiae, Rad50, Mre1...

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Détails bibliographiques
Auteurs principaux: Uanschou, Clemens, Siwiec, Tanja, Pedrosa-Harand, Andrea, Kerzendorfer, Claudia, Sanchez-Moran, Eugenio, Novatchkova, Maria, Akimcheva, Svetlana, Woglar, Alexander, Klein, Franz, Schlögelhofer, Peter
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140101/
https://ncbi.nlm.nih.gov/pubmed/18007598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601913
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