A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination

Genome stability relies on faithful DNA repair both in mitosis and in meiosis. Here, we report on a Caenorhabditis elegans protein that we found to be homologous to the mammalian repair-related protein CtIP and to the budding yeast Com1/Sae2 recombination protein. A com-1 mutant displays normal meio...

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Main Authors: Penkner, Alexandra, Portik-Dobos, Zsuzsanna, Tang, Lois, Schnabel, Ralf, Novatchkova, Maria, Jantsch, Verena, Loidl, Josef
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140103/
https://ncbi.nlm.nih.gov/pubmed/18007596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601916
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