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Mutations in Caenorhabditis elegans him-19 Show Meiotic Defects That Worsen with Age

From a screen for meiotic Caenorhabditis elegans mutants based on high incidence of males, we identified a novel gene, him-19, with multiple functions in prophase of meiosis I. Mutant him-19(jf6) animals show a reduction in pairing of homologous chromosomes and subsequent bivalent formation. Consist...

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Detalhes bibliográficos
Main Authors: Tang, Lois, Machacek, Thomas, Mamnun, Yasmine M., Penkner, Alexandra, Gloggnitzer, Jiradet, Wegrostek, Christina, Konrat, Robert, Jantsch, Michael F., Loidl, Josef, Jantsch, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836969/
https://ncbi.nlm.nih.gov/pubmed/20071466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0811
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