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A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene
Obligatory homologous recombination (HR) is required for chiasma formation and chromosome segregation in meiosis I. Meiotic HR is initiated by DNA double-strand breaks (DSBs), generated by Spo11, a homologue of the archaebacterial topoisomerase subunit Top6A. In Saccharomyces cerevisiae, Rad50, Mre1...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2140101/ https://ncbi.nlm.nih.gov/pubmed/18007598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601913 |
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