Desoxyepothilone B: An efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B

A new class of 16-membered macrolides, the epothilones (Epos), has been synthesized and evaluated for antitumor potential in vitro and in vivo. Recent studies in these and other laboratories showed that epothilones and paclitaxel (paclitaxel) share similar mechanisms of action in stabilizing microtu...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Chou, Ting-Chao, Zhang, Xiu-Guo, Balog, Aaron, Su, Dai-Shi, Meng, Dongfang, Savin, Kenneth, Bertino, Joseph R., Danishefsky, Samuel J.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC21392/
https://ncbi.nlm.nih.gov/pubmed/9689134
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы