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Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock

Mammalian 2-Cys peroxiredoxin II (Prx II) is a cellular peroxidase that eliminates endogenous H(2)O(2). The involvement of Prx II in the regulation of lipopolysaccharide (LPS) signaling is poorly understood. In this report, we show that LPS induces substantially enhanced inflammatory events, which i...

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Bibliografiske detaljer
Main Authors: Yang, Chul-Su, Lee, Dong-Seok, Song, Chang-Hwa, An, Se-Jin, Li, Shengjin, Kim, Jin-Man, Kim, Cuk Seong, Yoo, Dae Goon, Jeon, Byeong Hwa, Yang, Hee-Young, Lee, Tae-Hoon, Lee, Zee-Won, El-Benna, Jamel, Yu, Dae-Yeul, Jo, Eun-Kyeong
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137909/
https://ncbi.nlm.nih.gov/pubmed/17325201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061849
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