Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells

Mammalian 2-Cys peroxiredoxin (Prx) enzymes are overexpressed in most cancer tissues, but their specific signaling role in cancer progression is poorly understood. Here we demonstrate that Prx type II (PrxII) plays a tumor-promoting role in colorectal cancer by interacting with a poly(ADP-ribose) po...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kang, Dong Hoon, Lee, Doo Jae, Lee, Sunmi, Lee, So-Young, Jun, Yukyung, Kim, Yerin, Kim, Youngeun, Lee, Ju-Seog, Lee, Dae-Kee, Lee, Sanghyuk, Jho, Eek-Hoon, Yu, Dae-Yeul, Kang, Sang Won
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489516/
https://ncbi.nlm.nih.gov/pubmed/28659575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00054-0
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