Survival of APC-mutant colorectal cancer cells requires interaction between tankyrase and a thiol peroxidase, peroxiredoxin II

Overexpression of mammalian 2-Cys peroxiredoxin (Prx) enzymes is observed in most cancer tissues. Nevertheless, their specific roles in colorectal cancer (CRC) progression has yet to be fully elucidated. Here, a novel molecular mechanism by which PrxII/Tankyrase (TNKS) interaction mediates survival...

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Vydáno v:BMB Rep
Hlavní autoři: Kang, Dong Hoon, Lee, Joanna H.S., Kang, Sang Won
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2017
Témata:
Perspective
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595167/
https://ncbi.nlm.nih.gov/pubmed/28683851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.8.120
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