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Peroxiredoxin 2 Deficiency Exacerbates Atherosclerosis in Apolipoprotein E–Deficient Mice

RATIONALE: Peroxiredoxin 2 (Prdx2), a thiol-specific peroxidase, has been reported to regulate proinflammatory responses, vascular remodeling, and global oxidative stress. OBJECTIVE: Although Prdx2 has been proposed to retard atherosclerosis development, no direct evidence and mechanisms have been r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Circ Res
Hauptverfasser: Park, Jong-Gil, Yoo, Ji-Young, Jeong, Se-Jin, Choi, Jae-Hoon, Lee, Mi-Ran, Lee, Mi-Ni, Lee, Jeong Hwa, Kim, Hyoung Chin, Jo, Hanjoong, Yu, Dae-Yeul, Kang, Sang Won, Rhee, Sue Goo, Lee, Mun-Han, Oh, Goo Taeg
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474748/
https://ncbi.nlm.nih.gov/pubmed/21835911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.245530
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