The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock

Compound K (C-K), a protopanaxadiol ginsenoside metabolite, was previously shown to have immunomodulatory effects. Here, we describe a novel therapeutic role for C-K in the treatment of lethal sepsis through the modulation of Toll-like receptor (TLR) 4-associated signalling via glucocorticoid recept...

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Detalhes bibliográficos
Main Authors: Yang, Chul-Su, Ko, Sung-Ryong, Cho, Byung-Goo, Shin, Dong-Min, Yuk, Jae-Min, Li, Shengjin, Kim, Jin-Man, Evans, Ronald M, Jung, Jun-Sub, Song, Dong-Keun, Jo, Eun-Kyeong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918090/
https://ncbi.nlm.nih.gov/pubmed/18053081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2007.00181.x
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