α(E)β(7) integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

Various T cell adhesion molecules and their cognate receptors on target cells promote T cell receptor (TCR)–mediated cell killing. In this report, we demonstrate that the interaction of epithelial cell marker E-cadherin with integrin α(E)(CD103)β(7), often expressed by tumor-infiltrating lymphocytes...

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Autors principals: Floc'h, Audrey Le, Jalil, Abdelali, Vergnon, Isabelle, Chansac, Béatrice Le Maux, Lazar, Vladimir, Bismuth, Georges, Chouaib, Salem, Mami-Chouaib, Fathia
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137907/
https://ncbi.nlm.nih.gov/pubmed/17325197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061524
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